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On-line Access: 2024-12-30
Received: 2024-06-11
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Residual hyperglycemia after successful treatment of a patient with severe copper sulfate poisoning
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Ting LI, Yuan-qiang LU. Residual hyperglycemia after successful treatment of a patient with severe copper sulfate poisoning[J]. Journal of Zhejiang University Science B, 2024, 25(12): 1120-1124.
@article{title="Residual hyperglycemia after successful treatment of a patient with severe copper sulfate poisoning",
author="Ting LI, Yuan-qiang LU",
journal="Journal of Zhejiang University Science B",
volume="25",
number="12",
pages="1120-1124",
year="2024",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2400305"
}
%0 Journal Article
%T Residual hyperglycemia after successful treatment of a patient with severe copper sulfate poisoning
%A Ting LI
%A Yuan-qiang LU
%J Journal of Zhejiang University SCIENCE B
%V 25
%N 12
%P 1120-1124
%@ 1673-1581
%D 2024
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2400305
TY - JOUR
T1 - Residual hyperglycemia after successful treatment of a patient with severe copper sulfate poisoning
A1 - Ting LI
A1 - Yuan-qiang LU
J0 - Journal of Zhejiang University Science B
VL - 25
IS - 12
SP - 1120
EP - 1124
%@ 1673-1581
Y1 - 2024
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B2400305
Abstract: Copper sulfate is a frequently used copper compound in laboratory settings, with instances of poisoning being uncommon. A study conducted by the American Association of Poison Control Centers National Poison Data System found that only 140 individuals were exposed to copper compounds over the course of a year, with five cases being intentional (Gummin et al., 2023). Severe poisoning from copper sulfate can result in isolated gastrointestinal injury (Galust et al., 2023), intravascular hemolysis (Adline et al., 2024), rhabdomyolysis (Richards et al., 2020), and other symptoms documented in the literature. However, there have been no reports of long-term uncontrolled hyperglycemia in patients with copper sulfate poisoning. This case study documents the treatment approach for a patient with unexplained, long-term, uncontrolled hyperglycemia, alongside multiple organ dysfunction resulting from intentional ingestion of a large dose of copper sulfate. This case report details the long-term complications in a patients recovery from acute copper sulfate, highlighting the significance of ongoing monitoring and intervention.
[1]AdlineFA, ShanthiR, SivakumarMR, et al., 2024. In vitro immune analysis of serum from the hemolymph of the anomuran crab Albunea symmysta (Linnaeus, 1758) displayed diversified reactions. J Invertebr Pathol, 204:108098.
[2]BaiH, FangYK, CaoHB, et al., 2023. Inhibition of the BNIP3/NIX-dependent mitophagy aggravates copper-induced mitochondrial dysfunction in duck renal tubular epithelial cells. Environ Toxicol, 38(3):579-590.
[3]BanerjeeP, MohanAK, BaidH, et al., 2023. Off with the blues: therapeutic plasma exchange in a case of copper sulphate poisoning. Transfus Apher Sci, 62(6):103811.
[4]ChenJ, LiaoJZ, YuWL, et al., 2024. Copper toxicity in the liver of broiler chicken: insights from metabolomics and AMPK-mTOR mediated autophagy perspective. Poult Sci, 103(9):104011.
[5]DaryagashtM, MoosaviM, KhorsandiL, et al., 2023. Hepatoprotective and anti-hyperglycemic effects of ferulic acid in arsenic-exposed mice. Food Chem Toxicol, 178:113924.
[6]DuY, MouY, 2019. The role of plasmapheresis in treating lethal cupric sulfate poisoning. Am J Med Sci, 357(4):338-342.
[7]GalustH, SeltzerJA, HardinJR, et al., 2023. Campfire corrosive: isolated gastrointestinal injury following ingestion of copper salts. Am J Emerg Med, 70:210.e5-210.e8.
[8]GumminDD, MowryJB, BeuhlerMC, et al., 2023. 2022 Annual Report of the National Poison Data System® (NPDS) from America’s Poison Centers®: 40th Annual Report. Clin Toxicol (Phila), 61(10):717-939.
[9]JiangL, YangF, LiaoH, et al., 2024. Molybdenum and cadmium cause blood-testis barrier dysfunction through ROS-mediated NLRP3 inflammasome activation in sheep. Sci Total Environ, 906:167267.
[10]NahaK, SaravuK, ShastryBA, 2012. Blue vitriol poisoning: a 10-year experience in a tertiary care hospital. Clin Toxicol (Phila), 50(3):197-201.
[11]QinCF, YangYM, LuYQ, 2023. Perforation of the esophagus: an overlooked cause of chest pain as a complication of esophageal foreign bodies. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 24(5):455-457.
[12]RichardsJR, ScheerlinckPH, OwenKP, et al., 2020. Bodybuilding supplements leading to copper toxicity, encephalopathy, fulminant hepatic failure and rhabdomyolysis. Am J Emerg Med, 38(11):2487.e2481-2487.e2485.
[13]ShankarJA, KaurA, TyagiL, et al., 2023. Severe copper sulphate poisoning: a case rescued with plasmapheresis. Trop Doct, 53(2):327-328.
[14]TaoDY, WangY, LiuJF, et al., 2021. Mechanism of CuSO4 cytotoxicity in goat erythrocytes after high-level in vitro exposure to isotonic media. Ecotoxicol Environ Saf, 208:111730.
[15]TrigwellSM, RadfordPM, PageSR, et al., 2001. Islet glutamic acid decarboxylase modified by reactive oxygen species is recognized by antibodies from patients with type 1 diabetes mellitus. Clin Exp Immunol, 126(2):242-249.
[16]WangT, ChenXY, LongXH, et al., 2016. Copper nanoparticles and copper sulphate induced cytotoxicity in hepatocyte primary cultures of Epinephelus coioides. PLoS ONE, 11(2):e0149484.
[17]WangZD, LuX, YangYM, et al., 2023. Inflammatory granuloma of the trachea: a rare case with Epstin-Barr virus infection. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 24(6):539-542.
[18]WuHB, GuoHR, LiuH, et al., 2020. Copper sulfate-induced endoplasmic reticulum stress promotes hepatic apoptosis by activating CHOP, JNK and caspase-12 signaling pathways. Ecotoxicol Environ Saf, 191:110236.
[19]ZhangT, YangF, DaiXY, et al., 2023. Role of Caveolin-1 on the molybdenum and cadmium exposure induces pulmonary ferroptosis and fibrosis in the sheep. Environ Pollut, 334:122207.
[20]ZhangYL, LiGY, ZhaoYQ, et al., 2023. Inhibition of calcium imbalance protects hepatocytes from vanadium exposure-induced inflammation by mediating mitochondrial-associated endoplasmic reticulum membranes in ducks. Poult Sci, 102(12):103013.
[21]ZhaoM, WanJ, QinWZ, et al., 2023. A machine learning-based diagnosis modelling of type 2 diabetes mellitus with environmental metal exposure. Comput Methods Programs Biomed, 235:107537.
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