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Journal of Zhejiang University SCIENCE A 2003 Vol.4 No.2 P.228-231

http://doi.org/10.1631/jzus.2003.0228


TCD study of hemodynamic changes in PCA response to photic stimulation


Author(s):  ZHENG Xu-ning, ZHU Xiong-chao, XU Qiu-fang, HUANG Yi-ning, LIU Yang

Affiliation(s):  Department of Neurology, the first affiliated hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China; more

Corresponding email(s):   alexliu@med.uni-goettingen.de

Key Words:  Cerebral blood flow, Ultrasonography, Vasomotor reactivity, TCD (Transcranial Doppler)


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ZHENG Xu-ning, ZHU Xiong-chao, XU Qiu-fang, HUANG Yi-ning, LIU Yang. TCD study of hemodynamic changes in PCA response to photic stimulation[J]. Journal of Zhejiang University Science A, 2003, 4(2): 228-231.

@article{title="TCD study of hemodynamic changes in PCA response to photic stimulation",
author="ZHENG Xu-ning, ZHU Xiong-chao, XU Qiu-fang, HUANG Yi-ning, LIU Yang",
journal="Journal of Zhejiang University Science A",
volume="4",
number="2",
pages="228-231",
year="2003",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2003.0228"
}

%0 Journal Article
%T TCD study of hemodynamic changes in PCA response to photic stimulation
%A ZHENG Xu-ning
%A ZHU Xiong-chao
%A XU Qiu-fang
%A HUANG Yi-ning
%A LIU Yang
%J Journal of Zhejiang University SCIENCE A
%V 4
%N 2
%P 228-231
%@ 1869-1951
%D 2003
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2003.0228

TY - JOUR
T1 - TCD study of hemodynamic changes in PCA response to photic stimulation
A1 - ZHENG Xu-ning
A1 - ZHU Xiong-chao
A1 - XU Qiu-fang
A1 - HUANG Yi-ning
A1 - LIU Yang
J0 - Journal of Zhejiang University Science A
VL - 4
IS - 2
SP - 228
EP - 231
%@ 1869-1951
Y1 - 2003
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2003.0228


Abstract: 
Objectives: During visual stimulation, the elevated metabolism rate will couple with increase of blood flow velocity (BFV) in posterior cerebral artery (PCA). This study with TCD was aimed to investigate whether the coupling might change according to the different vasoneuronal conditions. Methods: Ninety-nine volunteers including 24 hypertension (HT) patients and 2 patients suffering from both HT and diabetes mellitus (DM) were enrolled in this trial. BFV and pulse indexes (PI) in P2 segments of PCA on both sides were monitored during visual stimulation. Results: In all subjects, Mean BFV increased and PI went down in response to visual stimulation. The percentages of changes (ΔV and ΔP) of both mean BFV and PI were larger in young group (<55 years old) than in old one (≥55 years old). There was significant positive correlation between ΔV and ΔP. Multivariated regression analysis did not show HT and DM, but age related to ΔV(ΔP). We did not find significant difference of ΔV(ΔP) between left and right sides. Conclusions: Blood flow velocity in PCA P2 segment increased due to decreased cerebrovascular resistance during visual stimulation and the response weakened with aging of the patient.

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