Full Text:   <2047>

CLC number: S859.83; S814.1

On-line Access: 

Received: 2002-09-03

Revision Accepted: 2003-01-08

Crosschecked: 0000-00-00

Cited: 13

Clicked: 4677

Citations:  Bibtex RefMan EndNote GB/T7714

-   Go to

Article info.
1. Reference List
Open peer comments

Journal of Zhejiang University SCIENCE A 2004 Vol.5 No.2 P.193-197

http://doi.org/10.1631/jzus.2004.0193


Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks


Author(s):  ZHANG Cai-qiao, QIAO Hui-li

Affiliation(s):  College of Animal Sciences, Zhejiang University, Hangzhou 310029, China; more

Corresponding email(s):   cqzhang@zju.edu.cn

Key Words:  Chicken, Polychlorinated biphenyls (PCBs), Spermatogenesis, Testosterone


Share this article to: More

ZHANG Cai-qiao, QIAO Hui-li. Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks[J]. Journal of Zhejiang University Science A, 2004, 5(2): 193-197.

@article{title="Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks",
author="ZHANG Cai-qiao, QIAO Hui-li",
journal="Journal of Zhejiang University Science A",
volume="5",
number="2",
pages="193-197",
year="2004",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2004.0193"
}

%0 Journal Article
%T Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks
%A ZHANG Cai-qiao
%A QIAO Hui-li
%J Journal of Zhejiang University SCIENCE A
%V 5
%N 2
%P 193-197
%@ 1869-1951
%D 2004
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2004.0193

TY - JOUR
T1 - Effect of polychlorinated biphenyls on spermatogenesis and testosterone secretion in adult cocks
A1 - ZHANG Cai-qiao
A1 - QIAO Hui-li
J0 - Journal of Zhejiang University Science A
VL - 5
IS - 2
SP - 193
EP - 197
%@ 1869-1951
Y1 - 2004
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2004.0193


Abstract: 
The effects of polychlorinated biphenyls (PCBs) on reproduction of adult cocks were studied by gavaging peanut oil or PCBs (Aroclor 1254, 50 mg/kg) once a week for six consecutive weeks. Physiological parameters were recorded and gonads were removed at the end of experiment for histological examination. The results showed that there was no significant difference between the control and treatment group in body weight, respiration rate, heart rate, body temperature, and the numbers of red and white blood cells. However, there was a marked decrease in the testicular weight and serum testosterone level after PCB treatment. Morphological studies manifested severe damage of the seminiferous tubules by PCB. The number of the germ cells at the different developmental stages was decreased and condensed nuclei were observed in most of these cells. This study revealed that the reproductive function of the adult cocks is sensitive to PCBs, which inhibited mainly spermatogenesis and testosterone secretion.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1] Andric, S.A., Kostic, T.S., Stojikovic, S.S., 2000. Inhibition of rat testicular steroidogenesis by a polychlorinated biphenyl mixture Aroclor 1248.Biol. Reprod.,62(6):1882-1888.

[2] Bartke, A., Williams, K.I., Dalterio, S., 1977. Effects of estrogens on testicular testosterone production in vitro.Biol. Reprod.,17(5):645-649.

[3] Bernard, A., Hermans, C., Broeckaert, F., De Poorter, G., De Cock, A., Houins, G., 1999. Food contamination by PCBs and dioxins.Nature,401(6750):231-231.

[4] Fang, C., Zhang, C., Qiao, H., Xia, G.L., Chen, Y.X., 2001. Sexual difference in gonadal development of chicken embryos after treatment of polychlorinated biphenyls.Chin. Sci. Bull.,46(22):1094-1097.

[5] Fang, C., Zhang, C., Xia, G., Yang, W., 2002. Damaging effect of polychlorinated biphenyls on chicken primordial germ cells.Reprod. Fertil. Dev.,14(3-4):177-183.

[6] Friedmann, A.S., 2002. Atrazine inhibition of testosterone production in rat males following peripubertal exposure. Reprod.Toxicol.,16(3):275-279.

[7] Fry, D.M., Toone, C.K., 1981. DDT-induce feminization of gull embryos.Science,213(4510):922-924.

[8] Hess, R.A., Bunick, D., Lee, K.H., Bahr, J., Taylor, J.A., Korach, K.S., Lubahn, D.B., 1997. A role for oestrogens in the male reproductive system.Nature,390(6659):509-512.

[9] Hoffman, D.J., Rice, C.P., Kubiak, T.J., 1996. PCBs and Dioxins in Birds.In: Beyer, W. N., Heinz, G. H., Remon, A.W., eds., Environmental Contaminants in Wildlife: Interpreting Tissue Concentrations, SETAC, Pensacola, FL, USA, p.165-207.

[10] Korach, K.S., 1994. Insights from the study of animals lacking functional estrogen receptor.Science,266(5190):1524-1527.

[11] Loomis, A.K., Thomas, P., 2000. Effects of Estrogens and xenoestrogens on androgen production by Atlantic croaker testis in vitro: evidence for a nongenomic action mediated by an estrogen membrane receptor.Biol. Reprod.,62(4):995-1004.

[12] Mably, T.A., Bjerke, D.L. , Moore, R.W., 1992. In utero and lactational exposure of male rats to 2,3,7,8-tetrech-lorodibenzo-p-dioxin.3.Effects on spermatogenesis and reproductive capability.Toxicol. Appl. Pharmacol,114(1):118-126.

[13] Pflieger-Bruss, S., Hanf, V., Behnisch, P., Hagenmaier, H., Rune, G.M., 1999. Effects of single polychlorinated biphenyls on the morphology of cultured rat seminiferi.Andrologia,31(2):77-82.

[14] Sangalang, G.B., Freeman, H.C., Crowell, R., 1981. Testicular abnormalities in cod (Gadus morhua) fed Aroclor 1254.Arch. Environ. Contam. Toxicol.,10(5):617-626.

[15] Tilson, H.A., Kodavanti, P.R.S., 1997. Neurochemical effects of polychlorinated biphenyls: an overview and identication of research needs.Neuro. Toxicol.,18(3):727-744.

[16] Yeowell, H.N., Waxman, D.J., Wadhera, A., Goldstein, J.A., 1987. Suppression of the constitutive, male specific rat hepatic cytochromo P450 2c and its mRNA by 3,4,5, 3',4',5'-hexachloro-biphenyl and 3-methlchplantrene.Mol. Pharmacol,32(3):340-347.

[17] Zhang, C.Q., Fang, C.G., Liu, L., Xia, G.L., Qiao, H.L., 2002. Disrupting effects of polychlorinated biphenyls on gonadal development and reproductive functions in chickens.J. Environ. Sci. Health,A37(4):509-519.

Open peer comments: Debate/Discuss/Question/Opinion

<1>

Please provide your name, email address and a comment





Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - 2022 Journal of Zhejiang University-SCIENCE