CLC number: Q95
On-line Access:
Received: 2008-02-17
Revision Accepted: 2008-04-22
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Da-lei ZHANG, Yu-ling MI, Kai-ming WANG, Wei-dong ZENG, Cai-qiao ZHANG. Attenuating effect of daidzein on polychlorinated biphenyls-induced oxidative toxicity in mouse testicular cells[J]. Journal of Zhejiang University Science B, 2008, 9(7): 567-571.
@article{title="Attenuating effect of daidzein on polychlorinated biphenyls-induced oxidative toxicity in mouse testicular cells",
author="Da-lei ZHANG, Yu-ling MI, Kai-ming WANG, Wei-dong ZENG, Cai-qiao ZHANG",
journal="Journal of Zhejiang University Science B",
volume="9",
number="7",
pages="567-571",
year="2008",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B0820048"
}
%0 Journal Article
%T Attenuating effect of daidzein on polychlorinated biphenyls-induced oxidative toxicity in mouse testicular cells
%A Da-lei ZHANG
%A Yu-ling MI
%A Kai-ming WANG
%A Wei-dong ZENG
%A Cai-qiao ZHANG
%J Journal of Zhejiang University SCIENCE B
%V 9
%N 7
%P 567-571
%@ 1673-1581
%D 2008
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0820048
TY - JOUR
T1 - Attenuating effect of daidzein on polychlorinated biphenyls-induced oxidative toxicity in mouse testicular cells
A1 - Da-lei ZHANG
A1 - Yu-ling MI
A1 - Kai-ming WANG
A1 - Wei-dong ZENG
A1 - Cai-qiao ZHANG
J0 - Journal of Zhejiang University Science B
VL - 9
IS - 7
SP - 567
EP - 571
%@ 1673-1581
Y1 - 2008
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B0820048
Abstract: The attenuating effect of daidzein (DAI) on oxidative toxicity induced by Aroclor 1254 (A1254) was investigated in mouse testicular cells. Cells were exposed to A1254 alone or with DAI. The oxidative damage was estimated by measuring malondialdehyde (MDA) formation, superoxide dismutase (SOD) activity and glutathione (GSH) content. Results show that A1254 induced a decrease of germ cell number, an elevation in thiobarbituric acid reactive substances (TBARS) but a decrease in SOD activity and GSH content. However, simultaneous supplementation with DAI decreased TBARS level and increased SOD activity and GSH content. Consequently, dietary DAI may restore the intracellular antioxidant system to attenuate the oxidative toxicity of A1254 in testicular cells.
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