Full Text:
<3129>
CLC number: O621.3
On-line Access:
Received: 2005-03-01
Revision Accepted: 2005-04-12
Crosschecked: 0000-00-00
Cited: 0
Clicked: 6500
A new germacranolide from Carpesium cernuum
| |||||||||||||
CAO Jian-xin, PAN Yuan-jiang, XU Chong-yang, HUANG Li-xia, MA Shu-hong, DAI Chang-liang, GAO Wan-wan. A new germacranolide from Carpesium cernuum[J]. Journal of Zhejiang University Science A, 2005, 6(7): 640-642.
@article{title="A new germacranolide from Carpesium cernuum",
author="CAO Jian-xin, PAN Yuan-jiang, XU Chong-yang, HUANG Li-xia, MA Shu-hong, DAI Chang-liang, GAO Wan-wan",
journal="Journal of Zhejiang University Science A",
volume="6",
number="7",
pages="640-642",
year="2005",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2005.A0640"
}
%0 Journal Article
%T A new germacranolide from Carpesium cernuum
%A CAO Jian-xin
%A PAN Yuan-jiang
%A XU Chong-yang
%A HUANG Li-xia
%A MA Shu-hong
%A DAI Chang-liang
%A GAO Wan-wan
%J Journal of Zhejiang University SCIENCE A
%V 6
%N 7
%P 640-642
%@ 1673-565X
%D 2005
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2005.A0640
TY - JOUR
T1 - A new germacranolide from Carpesium cernuum
A1 - CAO Jian-xin
A1 - PAN Yuan-jiang
A1 - XU Chong-yang
A1 - HUANG Li-xia
A1 - MA Shu-hong
A1 - DAI Chang-liang
A1 - GAO Wan-wan
J0 - Journal of Zhejiang University Science A
VL - 6
IS - 7
SP - 640
EP - 642
%@ 1673-565X
Y1 - 2005
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2005.A0640
Abstract: As a part of our interest in biologically active germacranolides from the genus Carpesium (compositae), we have investigated the constituents of %29&ck%5B%5D=abstract&ck%5B%5D=keyword'>%29&ck%5B%5D=abstract&ck%5B%5D=keyword'>Carpesium cernuum. This paper reports the isolation and structural elucidation of a new germacranolide, cernolide A (Compound 1), from the herb. The structure of Compound 1 was determined as 2α,3β-dihydroxy-9-angeloxygermacra-4-en-6,12-olide on the basis of spectral evidence. The skeleton of Compound 1 was elucidation by IR, MS, 1H and 13C NMR, COSY, HMQC and HMBC experiments. The stereochemistry of Compound 1 was deduced by ROESY spectral data. Finally, the procedures of extraction and isolation were described in detail.
[1] Dong, Y.F., Ding, Y.M., 1988. Sesquiterpene lactones from Carpesium abrotanoides. Zhiwu Xuebao, 30:71-75 (in Chinese).
[2] Kim, D.K., Baek, N.I., Choi, S.U., Lee, C.O., Lee, K.R., Lee, O.P., 1997. Four new cytotoxic germacranolides from Carpesium divaricatum. J. Nat. Prod., 60:1199-1202.
[3] Lin, Y.L., Ou, J.C., 1996. Napalolides A-D, four new sesquiterpene lactones from Carpesium nepalense. J. Nat. Prod., 59:991-993.
[4] Maruyama, M., 1990. Sesquiterpene lactones from Carpesium divaricatum. Phytochemistry, 29:547-550.
[5] Maruyama, M., Omura, S., 1977. Carpesiolin from Carpesium abrotanoides. Phytochemistry, 16:782-783.
[6] Masao, M., Akio, K., Kiyoko, S., 1983. Sesquiterpene lactones from Carpesium abrotanoides. Phytochemistry, 22:2273-2274.
[7] Yang, C., Wang, X., Shi, Y.P., Jia, Z.J., 2002. The study on the compounds of the aerial part of Carpesium cernuum. J. Lanzhou Univ. SCI, 38:61-66.
Open peer comments: Debate/Discuss/Question/Opinion
<1>
Ritesh@Phd student<riteshbiochem2006@gmail.com>
2010-12-03 15:28:52
Please provide me following article...
A new germacranolide from Carpesium cernuum
CAO Jian-xin, PAN Yuan-jiang, XU Chong-yang, HUANG Li-xia, MA Shu-hong, DAI Chang-liang, GAO Wan-wan
Department of Chemistry, Zhejiang University, Hangzhou 310027, China; Zhejiang Hisun Pharmaceutical Co., Ltd., Taizhou 318000, China