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Journal of Zhejiang University SCIENCE B 2006 Vol.7 No.6 P.429-435


Guava extract (Psidium guajava) alters the labelling of blood constituents with technetium-99m


Affiliation(s):  Department of Biophysics and Biometry, Institute of Biology Roberto Alcantara Gomes, University of Estate of Rio de Janeiro, Rio de Janeiro 20551030, Brazil; more

Corresponding email(s):   adenilso@uerj.br

Key Words:  Antioxidant, Blood constituents, Psidium guajava, Technetium-99m

ABREU P.R.C., ALMEIDA M.C., BERNARDO R.M., BERNARDO L.C., BRITO L.C., GARCIA E.A.C., FONSECA A.S., BERNARDO-FILHO M.. Guava extract (Psidium guajava) alters the labelling of blood constituents with technetium-99m[J]. Journal of Zhejiang University Science B, 2006, 7(6): 429-435.

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journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Guava extract (Psidium guajava) alters the labelling of blood constituents with technetium-99m
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2006.B0429

T1 - Guava extract (Psidium guajava) alters the labelling of blood constituents with technetium-99m
J0 - Journal of Zhejiang University Science B
VL - 7
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SP - 429
EP - 435
%@ 1673-1581
Y1 - 2006
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2006.B0429

Psidium guajava (guava) leaf is a phytotherapic used in folk medicine to treat gastrointestinal and respiratory disturbances and is used as anti-inflammatory medicine. In nuclear medicine, blood constituents (BC) are labelled with technetium-99m (99mTc) and used to image procedures. However, data have demonstrated that synthetic or natural drugs could modify the labelling of BC with 99mTc. The aim of this work was to evaluate the effects of aqueous extract of guava leaves on the labelling of BC with 99mTc. Blood samples of Wistar rats were incubated with different concentrations of guava extract and labelled with 99mTc after the percentage of incorporated radioactivity (%ATI) in BC was determined. The results suggest that aqueous guava extract could present antioxidant action and/or alters the membrane structures involved in ion transport into cells, thus decreasing the radiolabelling of BC with 99mTc. The data showed significant (P<0.05) alteration of ATI in BC from blood incubated with guava extract.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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