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Received: 2006-04-14

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.1 P.39-44

http://doi.org/10.1631/jzus.2007.B0039


FoxO4 is the main forkhead transcriptional factor localized in the gastrointestinal tracts of pigs


Author(s):  ZHOU Zhen-qi, WANG Tian, PAN Ling-mei, HUANG Rui-hua, SHI Fang-xiong

Affiliation(s):  College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China

Corresponding email(s):   fxshi@njau.edu.cn

Key Words:  Forkhead, FoxO, Gastrointestinal tract, Immunohistochemistry, Swine


ZHOU Zhen-qi, WANG Tian, PAN Ling-mei, HUANG Rui-hua, SHI Fang-xiong. FoxO4 is the main forkhead transcriptional factor localized in the gastrointestinal tracts of pigs[J]. Journal of Zhejiang University Science B, 2007, 8(1): 39-44.

@article{title="FoxO4 is the main forkhead transcriptional factor localized in the gastrointestinal tracts of pigs",
author="ZHOU Zhen-qi, WANG Tian, PAN Ling-mei, HUANG Rui-hua, SHI Fang-xiong",
journal="Journal of Zhejiang University Science B",
volume="8",
number="1",
pages="39-44",
year="2007",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2007.B0039"
}

%0 Journal Article
%T FoxO4 is the main forkhead transcriptional factor localized in the gastrointestinal tracts of pigs
%A ZHOU Zhen-qi
%A WANG Tian
%A PAN Ling-mei
%A HUANG Rui-hua
%A SHI Fang-xiong
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 1
%P 39-44
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0039

TY - JOUR
T1 - FoxO4 is the main forkhead transcriptional factor localized in the gastrointestinal tracts of pigs
A1 - ZHOU Zhen-qi
A1 - WANG Tian
A1 - PAN Ling-mei
A1 - HUANG Rui-hua
A1 - SHI Fang-xiong
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 1
SP - 39
EP - 44
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.B0039


Abstract: 
forkhead box (Fox) proteins play critical roles in the regulation of differentiation, proliferation, immunity and aging of cells. Most studies on Fox proteins are limited to cultured cells and rodent. The aim of the current study is to detect by immunohistrochemistry whether foxO1, foxO3a and foxO4 proteins are localized in the stomach and intestine of the pig. The results showed that foxO4 exists in the mucosa in all parts of the stomach and intestine; foxO3a exists mainly in the lamina propria and muscularis of some parts. However, foxO1 is not detectable in all parts of the stomach and intestine. Collectively, the results of the present study indicate that there exists a distinct expression pattern of Fox proteins, and that foxO4 is a primary forkhead transcriptional factor localized in the gastrointestinal tracts of the pig.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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