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Journal of Zhejiang University SCIENCE B 2008 Vol.9 No.3 P.192-196


Treatment of zinc deficiency without zinc fortification

Author(s):  Donald OBERLEAS, Barbara F. HARLAND

Affiliation(s):  Department of Nutrition and Food Science, Texas Technique University Emeritus, Lubbock, Texas 79423, USA; more

Corresponding email(s):   doberlea@aol.com

Key Words:  Zinc (Zn), Phytate, Phytase, Zinc deficiency, Zinc homeostasis

Donald OBERLEAS, Barbara F. HARLAND. Treatment of zinc deficiency without zinc fortification[J]. Journal of Zhejiang University Science B, 2008, 9(3): 192-196.

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author="Donald OBERLEAS, Barbara F. HARLAND",
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publisher="Zhejiang University Press & Springer",

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%A Barbara F. HARLAND
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0710632

T1 - Treatment of zinc deficiency without zinc fortification
A1 - Donald OBERLEAS
A1 - Barbara F. HARLAND
J0 - Journal of Zhejiang University Science B
VL - 9
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SP - 192
EP - 196
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B0710632

zinc (Zn) deficiency in animals became of interest until the 1950s. In this paper, progresses in researches on physiology of Zn deficiency in animals, phytate effect on bioavailability of Zn, and role of phytase in healing Zn deficiency of animals were reviewed. Several studies demonstrated that Zn is recycled via the pancreas; the problem of Zn deficiency was controlled by Zn homeostasis. The endogenous secretion of Zn is considered as an important factor influencing Zn deficiency, and the critical molar ratio is 10. phytate (inositol hexaphosphate) constituted up to 90% of the organically bound phosphorus in seeds. Great improvement has been made in recent years on isolating and measuring phytate, and its structure is clear. phytate is considered to reduce Zn bioavailability in animal. phytase is the enzyme that hydrolyzes phytate and is present in yeast, rye bran, wheat bran, barley, triticale, and many bacteria and fungi. Zinc nutrition and bioavailability can be enhanced by addition of phytase to animal feeds. Therefore, using phytase as supplements, the most prevalent Zn deficiency in animals may be effectively corrected without the mining and smelting of several tons of zinc daily needed to correct this deficiency by fortification worldwide.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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