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CLC number: TS207.5

On-line Access: 2012-07-05

Received: 2011-12-25

Revision Accepted: 2012-05-30

Crosschecked: 2012-06-17

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Journal of Zhejiang University SCIENCE B 2012 Vol.13 No.7 P.525-532


Recent developments in the detection of melamine

Author(s):  Yuan Liu, Ewen E. D. Todd, Qiang Zhang, Jiang-rong Shi, Xian-jin Liu

Affiliation(s):  Key Laboratory of Food Quality and Safety of Jiangsu Province, Nanjing 210014, China; more

Corresponding email(s):   liuyuan@jaas.ac.cn

Key Words:  Melamine, Detection, Confirmation methods, Screening methods, Sample pretreatment

Yuan Liu, Ewen E. D. Todd, Qiang Zhang, Jiang-rong Shi, Xian-jin Liu. Recent developments in the detection of melamine[J]. Journal of Zhejiang University Science B, 2012, 13(7): 525-532.

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T1 - Recent developments in the detection of melamine
A1 - Yuan Liu
A1 - Ewen E. D. Todd
A1 - Qiang Zhang
A1 - Jiang-rong Shi
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J0 - Journal of Zhejiang University Science B
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B1100389

In recent years, there were two reported outbreaks of food borne illness associated with melamine. The presence of melamine and its related compounds in milk, feed, and other foods has resulted in the need for reliable methods for the detection and accurate quantification of this class of contaminants. The sample pretreatment for melamine in a complex matrix usually involves a liquid extraction by a polar solvent, followed by a further clean-up with solid phase extraction. Analyses of melamine and related compounds are commonly carried out by liquid or gas chromatographic methods conjugated with mass spectrometry. Other innovative screening methods, which use antibodies, molecularly imprinted polymers, capillary electrophoresis, and gold nanoparticles, are also used to develop assays and biosensors to melamine. However, many of these methods have been hindered by matrix effects, the solubility of melamine-cyanuric acid complex, and background contamination. This article reviews recent developments for detecting melamine and discusses future directions.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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