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CLC number: S567

On-line Access: 2018-02-06

Received: 2016-10-05

Revision Accepted: 2017-05-04

Crosschecked: 2018-01-08

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Citations:  Bibtex RefMan EndNote GB/T7714

 ORCID:

Muhammad Imran

https://orcid.org/0000-0002-6830-396X

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Journal of Zhejiang University SCIENCE B 2018 Vol.19 No.2 P.120-129

http://doi.org/10.1631/jzus.B1600443


Phytochemical composition, biological potential and enzyme inhibition activity of Scandix pecten-veneris L.


Author(s):  Abdul Wahab, Syed Aleem Jan, Abdur Rauf, Zia ur Rehman, Zahid Khan, Aftab Ahmed, Fatima Syed, Sher Zaman Safi, Hamayun Khan, Muhammad Imran

Affiliation(s):  Department of Chemistry, Islamia College University, Peshawar-25120 KP, Pakistan; more

Corresponding email(s):   hamayun84@yahoo.com, imrancl@uop.edu.pk

Key Words:  Scandix pecten-veneris L., Phytochemical composition, Antioxidant activity, Antimicrobial potential, Enzyme inhibition


Abdul Wahab, Syed Aleem Jan, Abdur Rauf, Zia ur Rehman, Zahid Khan, Aftab Ahmed, Fatima Syed, Sher Zaman Safi, Hamayun Khan, Muhammad Imran. Phytochemical composition, biological potential and enzyme inhibition activity of Scandix pecten-veneris L.[J]. Journal of Zhejiang University Science B, 2018, 19(2): 120-129.

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author="Abdul Wahab, Syed Aleem Jan, Abdur Rauf, Zia ur Rehman, Zahid Khan, Aftab Ahmed, Fatima Syed, Sher Zaman Safi, Hamayun Khan, Muhammad Imran",
journal="Journal of Zhejiang University Science B",
volume="19",
number="2",
pages="120-129",
year="2018",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1600443"
}

%0 Journal Article
%T Phytochemical composition, biological potential and enzyme inhibition activity of Scandix pecten-veneris L.
%A Abdul Wahab
%A Syed Aleem Jan
%A Abdur Rauf
%A Zia ur Rehman
%A Zahid Khan
%A Aftab Ahmed
%A Fatima Syed
%A Sher Zaman Safi
%A Hamayun Khan
%A Muhammad Imran
%J Journal of Zhejiang University SCIENCE B
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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1600443

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T1 - Phytochemical composition, biological potential and enzyme inhibition activity of Scandix pecten-veneris L.
A1 - Abdul Wahab
A1 - Syed Aleem Jan
A1 - Abdur Rauf
A1 - Zia ur Rehman
A1 - Zahid Khan
A1 - Aftab Ahmed
A1 - Fatima Syed
A1 - Sher Zaman Safi
A1 - Hamayun Khan
A1 - Muhammad Imran
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 2
SP - 120
EP - 129
%@ 1673-1581
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PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1600443


Abstract: 
Objective: Scandix pecten-veneris L. is a less studied wild edible herb and is considered an extinct plant species in many parts of the world. This study was designed to evaluate its phytochemical composition and biological potential of S. pecten-veneris L. Methods: Phytochemicals including alkaloids, flavonoids, polyphenols, and tannins were determined in extracts of S. pecten-veneris. antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), while reducing power was tested by ferric reducing/antioxidant power (FRAP) assay. Antimicrobial activity against seven bacterial and four fungal strains was evaluated using agar well diffusion assay. Enzymes inhibition study was performed for urease, phosphodiesterase-I, and catalase-II. Results: S. pecten-veneris showed moderate antiradical activity and reducing potential of hydroxyl radicals to about 20% of the initial value. The antioxidant activity of various extracts of S. pecten-veneris showed a linear correlation with total phenolic contents in the order of water>n-butanol>chloroform>ethyl acetate>methanol extracts. S. pecten-veneris leaves showed the highest inhibitory activity against Staphylococcus aureus while the highest antifungal activity was observed against Candida albicans. The plant extract was most potent against urease enzymes but showed moderate activity against phosphodiestrase-I and carbonic anhydrase-II. Conclusions: Our data demonstrate that in addition to its culinary uses, S. pecten-veneris has good medicinal potential and hence could be used for treating some specific health ailments.

Scandix pecten-veneris L.的植物素、生物学潜力及酶抑制活性研究

目的:本研究旨在测定Scandix pecten-veneris L.的植物素和评价其生物学潜力.
方法:测定S. pecten-veneris提取物中植物素的含量,包括生物碱、黄酮、多酚和单宁.使用2,2-二苯基-1-苦肼基(DPPH)测定抗氧化活性;同时通过铁还原/抗氧化能力(FRAP)测定还原能力;使用琼脂扩散测定法评价对七种细菌和四种真菌菌株的抗微生物活性.同时,对脲酶、磷酸二酯酶-I和过氧化氢酶-II进行酶抑制研究.
结论:沙门氏菌显示出适度的抗自由基活性;羟基自由基的潜能降至初始值的20%左右.S. pecten-veneris多种提取物的抗氧化活性与总酚含量呈线性相关.S. pecten-veneris叶对金黄色葡萄球菌表现出最高的抑制活性;对白色念珠菌表现出到最高的抗真菌活性.植物提取物对脲酶的活性最有效;对磷酸二酯酶-I和碳酸酐酶-II显示出中等活性.结果表明,S. pecten-veneris具有良好的药用潜力,可用于治疗一些特定的疾病.

关键词:Scandix pecten-veneris L.;植物素;抗氧化活性;抑菌能力;酶抑制

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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