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Received: 2020-11-03

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Zhaofeng LIANG


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Journal of Zhejiang University SCIENCE B 2021 Vol.22 No.5 P.341-347


Exosomes in bladder cancer: novel biomarkers and targets

Author(s):  Hao GENG, Qingchen ZHOU, Wenhao GUO, Ling LU, Liangkuan BI, Yi WANG, Jie MIN, Dexin YU, Zhaofeng LIANG

Affiliation(s):  Department of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230032, China; more

Corresponding email(s):   dxyu@ahmu.edu.cn, liangzhaofeng@ujs.edu.cn

Key Words:  Exosome, Bladder cancer, Function, Clinical application, Biomarker

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Hao GENG, Qingchen ZHOU, Wenhao GUO, Ling LU, Liangkuan BI, Yi WANG, Jie MIN, Dexin YU, Zhaofeng LIANG. Exosomes in bladder cancer: novel biomarkers and targets[J]. Journal of Zhejiang University Science B, 2021, 22(5): 341-347.

@article{title="Exosomes in bladder cancer: novel biomarkers and targets",
author="Hao GENG, Qingchen ZHOU, Wenhao GUO, Ling LU, Liangkuan BI, Yi WANG, Jie MIN, Dexin YU, Zhaofeng LIANG",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Exosomes in bladder cancer: novel biomarkers and targets
%A Qingchen ZHOU
%A Wenhao GUO
%A Ling LU
%A Liangkuan BI
%A Jie MIN
%A Dexin YU
%A Zhaofeng LIANG
%J Journal of Zhejiang University SCIENCE B
%V 22
%N 5
%P 341-347
%@ 1673-1581
%D 2021
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2000711

T1 - Exosomes in bladder cancer: novel biomarkers and targets
A1 - Hao GENG
A1 - Qingchen ZHOU
A1 - Wenhao GUO
A1 - Ling LU
A1 - Liangkuan BI
A1 - Yi WANG
A1 - Jie MIN
A1 - Dexin YU
A1 - Zhaofeng LIANG
J0 - Journal of Zhejiang University Science B
VL - 22
IS - 5
SP - 341
EP - 347
%@ 1673-1581
Y1 - 2021
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2000711

exosomes are nanometer-sized vesicles that contain various types of biologically active components, including proteins, nucleic acids, carbohydrates, and lipids, which vary with the type and physiological state of the cell. In recent years, several studies have showed that exosomes can provide new non-invasive diagnostic and prognostic biomarkers in patients affected by cancers, including bladder cancer (BC), and the lipid bilayer membrane structure makes exosomes as promising delivery vehicles for therapeutic applications. exosomes have the characteristics of high abundance, high stability, tissue specificity, and wide distribution in body fluids, and are secreted as various types by cells in different states, thereby possessing great potential as biomarkers for BC. Herein, we briefly summarize the functions and roles of exosomes in the occurrence and development of BC and the current progress of research on exosomes in BC, while focusing on potential clinical applications of the diagnosis, treatment, and prognosis of BC.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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