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Numerical investigation of resolution in a single emitter localization-based imaging system
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Yueying WANG1, Yiwen HU1, Yuehan ZHAO1, Cuifang KUANG1,2,3, Xiang HAO1,2. Numerical investigation of resolution in a single emitter localization-based imaging system[J]. Frontiers of Information Technology & Electronic Engineering, 1998, -1(-1): .
@article{title="Numerical investigation of resolution in a single emitter localization-based imaging system",
author="Yueying WANG1, Yiwen HU1, Yuehan ZHAO1, Cuifang KUANG1,2,3, Xiang HAO1,2",
journal="Frontiers of Information Technology & Electronic Engineering",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/FITEE.2500015"
}
%0 Journal Article
%T Numerical investigation of resolution in a single emitter localization-based imaging system
%A Yueying WANG1
%A Yiwen HU1
%A Yuehan ZHAO1
%A Cuifang KUANG1
%A 2
%A 3
%A Xiang HAO1
%A 2
%J Journal of Zhejiang University SCIENCE C
%V -1
%N -1
%P
%@ 2095-9184
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/FITEE.2500015
TY - JOUR
T1 - Numerical investigation of resolution in a single emitter localization-based imaging system
A1 - Yueying WANG1
A1 - Yiwen HU1
A1 - Yuehan ZHAO1
A1 - Cuifang KUANG1
A1 - 2
A1 - 3
A1 - Xiang HAO1
A1 - 2
J0 - Journal of Zhejiang University Science C
VL - -1
IS - -1
SP -
EP -
%@ 2095-9184
Y1 - 1998
PB - Zhejiang University Press & Springer
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DOI - 10.1631/FITEE.2500015
Abstract: In this paper, we numerically analyze the factors determining localization precision and resolution in single emitter localization-based imaging systems. While previous studies considered a limited set of parameters, our numerical approach incorporates additional parameters with significant reference value, yielding a more comprehensive analysis of the results. We differentiate between the effects of additive and multiplicative noise on localization precision using numerical modeling. Additionally, we take the influence of sampling frequency into account and compute the optimal sampling frequency for varying resolution requirements. Leveraging a suite of derived equations, we systematically simulate and quantify how variations in these parameters influence system performance. Furthermore, we provide guidelines for optimizing signal-to-noise ratio (SNR) requirements and pixel size selection based on point spread function (PSF) width in single emitter localization-based imaging systems. This numerically driven research establishes a solid foundation, offering critical insights for the analysis of more complex imaging systems.
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