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Abstract: heart rate variability (HRV) analysis is affected by ectopic beats. An efficient method was proposed to deal with the ectopic beats. The method was based on trend correlation of the heart timing signal. Predictor of R-R interval (RRI) value at ectopic beat time was constructed by the weight calculation and the slope estimation of preceding normal RRI. The type of ectopic beat was detected and replaced by the predictor of RRI. The performance of the simulated signal after ectopic correction was tested by the standard value using power spectrum density (PSD) estimation, whereas the results of clinical data with ectopic beats were compared with the adjacent ectopic-free data. The result showed the frequency indexes after ectopy corrected had less error than other methods with the test of simulated signal and clinical data. It indicated our method could improve the PSD estimation in HRV analysis. The method had advantages of high accuracy and real time properties to recover the sinus node modulation.

[1]Acar, B., Savelieva, I., Hemingway, H., Malik, M., 2000. Automatic ectopic beat elimination in short-term heart rate variability measurement. Comput. Methods Programs Biomed., 63(2):123-131.

[2]Amar, D., Zhang, H., Miodownik, S., Kadish, A.H., 2003. Competing autonomic mechanisms precede the onset of postoperative atrial fibrillation. J. Am. Coll. Cardiol., 42(7):1262-1268.

[3]Bettoni, M., Zimmermann, M., 2002. Autonomic tone variations before the onset of paroxysmal atrial fibrillation. Circulation, 105(23):2753-2759.

[4]Camm, A.J., Malik, M., Bigger, J.T., Breithardt, G., Cerutti, S., Cohen, R.J., Coumel, P., Fallen, E.L., Kennedy, H.L., Kleiger, R.E., et al., 1996. Heart rate variability: standards of measurement, physiological interpretation, and clinical use. Circulation, 93(5):1043-1065.

[5]Colak, O.H., 2009. Preprocessing effects in time-frequency distributions and spectral analysis of heart rate variability. Digital Signal Process., 19(4):731-739.

[6]Dimmer, C., Tavernier, R., Gjorgov, N., van Nooten, G., Clement, D.L., Jordaens, L., 1998. Variations of autonomic tone preceding onset of atrial fibrillation after coronary artery bypass grafting. Am. J. Cardiol., 82(1):22-25.

[7]Huang, J.L., Wen, Z.C., Lee, W.L., Chang, M.S., Chen, S.A., 1998. Changes of autonomic tone before the onset of paroxysmal atrial fibrillation. Int. J. Cardiol., 66(3):275-283.

[8]Kim, K.K., Kim, J.S., Lim, Y.G., Park, K.S., 2009. The effect of missing RR-interval data on heart rate variability analysis in the frequency domain. Physiol. Meas., 30(10):1039-1050.

[9]Li, H., Ma, X.Q., Ye, F., Zhang, J., Zhou, X., Wang, Z.H., Li, Y.M., Zhang, G.Y., 2009. Expressions of cardiac sympathetic norepinephrine transporter and β₁-adrenergic receptor decreased in aged rats. J. Zhejiang Univ.-Sci. B, 10(3):203-210.

[10]Lombardi, F., Tarricone, D., Tundo, F., Colombo, F., Belletti, S., Fiorentini, C., 2004. Autonomic nervous system and paroxysmal atrial fibrillation: study based on the analysis of RR interval changes before, during and after paroysmal atrial fibrillation. Eur. Heart J., 25(14):1242-1248.

[11]Maestri, R., Raczak, G., Danilowicz-Szymanowicz, L., Torunski, A., Sukiennik, A., Kubica, J., La Rovere, M.T., Pinna, G.D., 2010. Reliability of heart rate variability measurements in patients with a history of myocardial infarction. Clin. Sci., 118(3):195-201.

[12]Mateo, J., Laguna, P., 2003. Analysis of heart rate variability in the presence of ectopic beats using the heart timing signal. IEEE Trans. Biomed. Eng., 50(3):334-343.

[13]Mitov, I.P., 1998. A method for assessment and processing of biomedical signals containing trend and periodic components. Med. Eng. Phys., 20(9):660-668.

[14]Miyakoshi, M., Ikeda, T., Miwa, Y., Sakaki, K., Ishiguro, H., Abe, A., Tsukada, T., Mera, H., Yusu, S., Yoshino, H., 2009. Quantitative assessment of cibenzoline administration for vagally mediated paroxysmal atrial fibrillation using frequency-domain heart rate variability analysis. J. Cardiol., 54(1):86-92.

[15]Myers, G.A., Martin, G.J., Magin, N.M., Barnett, P.S., Schaad, J.W., Weiss, J.S., Lesch, M., Sigher, D.H., 1986. Power spectral analysis of heart rate variability in sudden cardiac death: comparison to other methods. IEEE Trans. Biomed. Eng., 33(12):1149-1156.

[16]Myers, G., Workman, M., Birkett, C., Ferguson, D., Kienzle, M., 1992. Problems in measuring heart rate variability of patients with congestive heart failure. J. Electrocardiol., 25:214-219.

[17]Ovreiu, M., Nair, B.G., Xu, M., Bakri, M.H., Li, L., Wazni, O., Fahmy, T., Petre, J., Starr, N.J., Sessler, D.I., et al., 2008. Electrocardiographic activity before onset of postoperative atrial fibrillation in cardiac surgery patients. Pacing Clin. Electrophysiol., 31(11):1371-1382.

[18]Sapoznikov, D., Luria, M.H., Mahler, Y., Gostman, M.S., 1992. Computer-processing of artifact and arrhythmias in heart-rate-variability analysis. Comput. Methods Programs Biomed., 39(1-2):75-84.

[19]Solem, K., Laguna, P., Sornmo, L., 2006. An efficient method for handling ectopic beats using the heart timing signal. IEEE Trans. Biomed. Eng., 53(1):13-20.

[20]Taddei, A., Distante, G., Emdin, M., Pisani, P., Moody, G.B., Zeelenberg, C., Marchesi, C., 1992. The European ST-T database: standard for evaluating systems for the analysis of ST-T changes in ambulatory electrocardiography. Eur. Heart J., 13(9):1164-1172.

[21]Tarvainen, M.P., Ranta-aho, P.O., Karjalainen, P.A., 2002. An advanced detrending method with application to HRV analysis. IEEE Trans. Biomed. Eng., 49(2):172-175.

[22]van Schelven, L.J., Oey, P.L., Klein, I.H.I., Barnas, M.G.W., Blankestijn, P.J., Wieneke, G.H., 2000. Observer variations in short period spectral analysis of heart rate variability. J. Autonom. Nerv. Syst., 79(2-3):144-148.

[23]Yamada, T., Yoshida, N., Murakami, Y., Okada, T., Yoshida, Y., Muto, M., Inden, Y., Murohara, T., 2009. Vagal modification can be a valid predictor of late recurrence of paroxysmal atrial fibrillation independent of the pulmonary vein isolation technique. Circ. J., 73(9):1606-1611.

[24]Zimmermann, M., Kalusche, D., 2001. Fluctuation in autonomic tone is a major determinant of sustained atrial arrhythmias in patients with focal ectopy originating from the pulmonary veins. J. Cardiovasc. Electrophysiol., 12(3):285-291.