Full Text:
<2751>
CLC number: X383
On-line Access:
Received: 2003-09-30
Revision Accepted: 2004-03-24
Crosschecked: 0000-00-00
Cited: 2
Clicked: 5047
Cleaner and convenient preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol
| |||||||||||||
WEN Yue-zhong, FANG Zhao-hua, LIU Wei-ping. Cleaner and convenient preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol[J]. Journal of Zhejiang University Science A, 2004, 5(8): 956-959.
@article{title="Cleaner and convenient preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol",
author="WEN Yue-zhong, FANG Zhao-hua, LIU Wei-ping",
journal="Journal of Zhejiang University Science A",
volume="5",
number="8",
pages="956-959",
year="2004",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2004.0956"
}
%0 Journal Article
%T Cleaner and convenient preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol
%A WEN Yue-zhong
%A FANG Zhao-hua
%A LIU Wei-ping
%J Journal of Zhejiang University SCIENCE A
%V 5
%N 8
%P 956-959
%@ 1869-1951
%D 2004
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2004.0956
TY - JOUR
T1 - Cleaner and convenient preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol
A1 - WEN Yue-zhong
A1 - FANG Zhao-hua
A1 - LIU Wei-ping
J0 - Journal of Zhejiang University Science A
VL - 5
IS - 8
SP - 956
EP - 959
%@ 1869-1951
Y1 - 2004
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2004.0956
Abstract: Environmental concerns have highlighted the need of cleaner technologies. A cleaner, convenient and selective technology has been developed for the preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol (DPMP) from 2-methyl-benzene-1,3-diol in water as solvent. The isolated yield of DPMP is up to 86% in good selectivity. The product structure was characterized by conventional methods, 1H-NMR and MS. This technology belongs to the modern concept of environmentally friendly low wastes or non-wastes technology (LWNWT).
[1] Lin, J., Huang, H., 1992. Mono-alkylation of 4,4’-biphenyldiol. Chinese Journal of Applied Chemistry, 9(6):110-112 (in Chinese).
[2] Mckillop, A., Fiaud, J.C., Hug, R.P., 1974. The use of phase-transfer catalysis for the synthesis of phenol ethers. Tetrahedron, 30:1379-1382.
[3] Muthusburamanian, L., Rao, V.S.S., Mitra, R., 2003. Convenient synthesis of methylene biothiocyanate as microbiocide. Journal of Cleaner Production, 11:695-693.
[4] Rao, J.R., Chandrababu, N.K., Maralidharan, C., Nair, B.U., Ramasami, P.G., Rao, T., 2003. Recouping the waste: a way forward for cleaner leather processing. Journal of Cleaner Production, 11:591-599.
[5] Xiao, G., Chong, Y., Hong, T., 1999. Diethlyeneglycol monobutylether synthesized by diethlyeneglycol etheration. Journal of Fushun Petroleum Institute, 19(1):3-5 (in Chinese).
[6] Zhao, Z.Z., Zhou, J., Lu, G., 1984. The Protection Groups in Organic Reactions. Science Press, Beijing (in Chinese).
Open peer comments: Debate/Discuss/Question/Opinion
<1>