Similar articles

Abstract: This study investigated the putative protective effects of supplemental 2-aminoethane sulfonic acid (taurine) and reduced housing density on renal function in laying hens. We randomly assigned fifteen thousand green-shell laying hens into three groups: a free range group, a low-density caged group, and a high-density caged group. Each group was further divided equally into a control group (C) and a taurine treatment group (T). After 15 d, we analyzed histological changes in kidney cells, inflammatory mediator levels, oxidation and anti-oxidation levels. Experimental data revealed taurine supplementation, and rearing free range or in low-density housing can lessen morphological renal damage, inflammatory mediator levels, and oxidation levels and increase anti-oxidation levels. Our data demonstrate that taurine supplementation and a reduction in housing density can ameliorate renal impairment, increase productivity, enhance health, and promote welfare in laying hens.

日粮中添加牛磺酸对不同饲养方式蛋鸡肾脏功能的影响

[1]Abbas, A.K., Murphy, K.M., Sher, A., 1996. Functional diversity of helper T lymphocytes. Nature, 383(6603):787-793.

[2]Al-Saady, N., Leatham, E., Gupta, S., et al., 1999. Monocyte expression of tissue factor and adhesion molecules: the link with accelerated coronary artery disease in patients with chronic renal failure. Heart, 81(2):134-140.

[3]Ansquer, J., Foucher, C., Aubonnet, P., et al., 2009. Fibrates and microvascular complications in diabetes-insight from the FIELD study. Curr. Pharm. Design, 15(5):537-552.

[4]Atherton, J.C., 2006. Role of the kidney in acid-base balance. Anaesth. Intens. Care Med., 7(7):276-278.

[5]Baker, R.G., Hayden, M.S., Ghosh, S., 2011. NF-κB, inflammation, and metabolic disease. Cell Metab., 13(1):11-22.

[6]Buijs, S., van Poucke, E., van Dongen, S., et al., 2012. The influence of stocking density on broiler chicken bone quality and fluctuating asymmetry. Poult. Sci., 91(8):1759-1767.

[7]Burt, D., 2002. Applications of biotechnology in the poultry industry. Worlds Poult. Sci. J., 58:5-13.

[8]Chesney, R.W., Han, X., Patters, A.B., 2010. Taurine and the renal system. J. Biomed. Sci., 17(Suppl. 1):S4.

[9]Chowdhry, S., Nazmy, M.H., Meakin, P.J., et al., 2010. Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis. Free Radical Biol. Med., 48(2):357-371.

[10]Cirillo, P., Sato, W., Reungjui, S., et al., 2006. Uric acid, the metabolic syndrome, and renal disease. J. Am. Soc. Nephrol., 17(12 Suppl. 3):S165-S168.

[11]Crews, F.T., Bechara, R., Brown, L.A., et al., 2006. Cytokines and alcohol. Alcohol Clin. Exp. Res., 30(4):720-730.

[12]Dai, B., Zhang, Y., Ma, Z., et al., 2015. Influence of dietary taurine and housing density on oviduct function in laying hens. J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.), 16(6):456-464.

[13]Das, J., Sil, P.C., 2012. Taurine ameliorates alloxan-induced diabetic renal injury, oxidative stress-related signaling pathways and apoptosis in rats. Amino Acids, 43(4):1509-1523.

[14]Das, J., Roy, A., Sil, P.C., 2012. Mechanism of the protective action of taurine in toxin and drug induced organ pathophysiology and diabetic complications: a review. Food Funct., 3(12):1251-1264.

[15]Davis, G., Anderson, K., Carroll, A., 2000. The effects of long-term caging and molt of Single Comb White Leghorn hens on heterophil to lymphocyte ratios, corticosterone and thyroid hormones. Poult. Sci., 79(4):514-518.

[16]Dawson, T.J., Maloney, S.K., Skadhauge, E., 1991. The role of the kidney in electrolyte and nitrogen excretion in a large flightless bird, the emu, during different osmotic regimes, including dehydration and nesting. J. Comp. Physiol. B, 161(2):165-171.

[17]Deiana, M., Incani, A., Rosa, A., et al., 2008. Protective effect of hydroxytyrosol and its metabolite homovanillic alcohol on H₂O₂ induced lipid peroxidation in renal tubular epithelial cells. Food Chem. Toxicol., 46(9):2984-2990.

[18]Gaucher, D., Arnault, E., Husson, Z., et al., 2012. Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells. Amino Acids, 43(5):1979-1993.

[19]Guan, Y.F., Breyer, M.D., 2001. Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease. Kidney Int., 60(1):14-30.

[20]Hamden, K., Carreau, S., Jamoussi, K., et al., 2009. 1α, 25 Dihydroxyvitamin D3: therapeutic and preventive effects against oxidative stress, hepatic, pancreatic and renal injury in alloxan-induced diabetes in rats. J. Nutr. Sci. Vitaminol., 55(3):215-222.

[21]Hanna, J., Chahine, R., Aftimos, G., et al., 2004. Protective effect of taurine against free radicals damage in the rat myocardium. Exp. Toxicol. Pathol., 56(3):189-194.

[22]He, G., Karin, M., 2011. NF-κB and STAT3—key players in liver inflammation and cancer. Cell Res., 21(1):159-168.

[23]Hu, Q.H., Wang, C., Li, J.M., et al., 2009. Allopurinol, rutin, and quercetin attenuate hyperuricemia and renal dysfunction in rats induced by fructose intake: renal organic ion transporter involvement. Am. J. Physiol.-Renal., 297(4):F1080-F1091.

[24]Kadam, S., Prabhasankar, P., 2010. Marine foods as functional ingredients in bakery and pasta products. Food Res. Int., 43(8):1975-1980.

[25]Kaneko, N., Sugioka, T., Sakurai, H., 2007. Aluminum compounds enhance lipid peroxidation in liposomes: insight into cellular damage caused by oxidative stress. J. Inorganic. Biochem., 101(6):967-975.

[26]Keller, S.A., Moore, C.C., Evans, S.L., et al., 2011. Activated protein C alters inflammation and protects renal function in sepsis. J. Surg. Res., 168(1):e103-e109.

[27]Kumar, A., Takada, Y., Boriek, A.M., et al., 2004. Nuclear factor-κB: its role in health and disease. J. Mol. Med., 82(7):434-448.

[28]Lakshmi Devi, S., Anuradha, C., 2010. Mitochondrial damage, cytotoxicity and apoptosis in iron-potentiated alcoholic liver fibrosis: amelioration by taurine. Amino Acids, 38(3):869-879.

[29]Lin, S., Yang, J., Wu, G., et al., 2010. Preventive effect of taurine on experimental type II diabetic nephropathy. J. Biomed. Sci., 17(Suppl. 1):S46.

[30]Miao, J.F., Zhang, Y.S., Huang, G.Q., et al., 2009. Polysaccharide nucleic acid of bacillus calmette guerin modulates Th1/Th2 cytokine gene expression in lipopolysaccharide-induced mastitis in rats. Agric. Sci. China, 8(8):1010-1018.

[31]Miao, J.F., Zhang, J.Q., Ma, Z.L., et al., 2013. The role of NADPH oxidase in taurine attenuation of Streptococcus uberis-induced mastitis in rats. Int. Immunopharmacol., 16(4):429-435.

[32]Moinuddin, I., Leehey, D.J., 2008. A comparison of aerobic exercise and resistance training in patients with and without chronic kidney disease. Adv. Chronic Kidney Dis., 15(1):83-96.

[33]Mozaffari, M., Patel, C., Abdelsayed, R., et al., 2006. Accelerated NaCl-induced hypertension in taurine-deficient rat: role of renal function. Kidney Int., 70(2):329-337.

[34]Nakagawa, T., Hu, H., Zharikov, S., et al., 2006. A causal role for uric acid in fructose-induced metabolic syndrome. Am. J. Physiol. Renal Physiol., 290(3):F625-F631.

[35]Nirala, S.K., Bhadauria, M., 2008. Propolis reverses acetaminophen induced acute hepatorenal alterations: a biochemical and histopathological approach. Arch. Pharm. Res., 31(4):451-461.

[36]Nirala, S.K., Bhadauria, M., Shukla, S., et al., 2008. Pharmacological intervention of tiferron and propolis to alleviate beryllium-induced hepatorenal toxicity. Fund. Clin. Pharmacol., 22(4):403-415.

[37]NRC (National Research Council), 1994. Committee on Rangeland Classification. Rangeland Health: New Methods to Classify, Inventory, and Monitor Rangelands. National Academies Press.

[38]Oberg, B.P., Mcmenamin, E., Lucas, F.L., et al., 2004. Increased prevalence of oxidant stress and inflammation in patients with moderate to severe chronic kidney disease. Kidney Int., 65(3):1009-1016.

[39]Parikh, V., Khan, M.M., Mahadik, S.P., 2003. Differential effects of antipsychotics on expression of antioxidant enzymes and membrane lipid peroxidation in rat brain. J. Psychiatr. Res., 37(1):43-51.

[40]Ridder, D., Schwaninger, M., 2009. NF-κB signaling in cerebral ischemia. Neuroscience, 158(3):995-1006.

[41]Robins, A., Phillips, C., 2011. International approaches to the welfare of meat chickens. Worlds Poult. Sci. J., 67(2):351-369.

[42]Rodrigo, R., Rivera, G., 2002. Renal damage mediated by oxidative stress: a hypothesis of protective effects of red wine. Free Radical. Biol. Med., 33(3):409-422.

[43]Rouach, H., Fataccioli, V., Gentil, M., et al., 1997. Effect of chronic ethanol feeding on lipid peroxidation and protein oxidation in relation to liver pathology. Hepatology, 25(2):351-355.

[44]Singh, D., Kaur, R., Chander, V., et al., 2006. Antioxidants in the prevention of renal disease. J. Med. Food, 9(4):443-450.

[45]Sun, M., Zhao, Y., Gu, Y., et al., 2012. Anti-inflammatory mechanism of taurine against ischemic stroke is related to down-regulation of PARP and NF-κB. Amino Acids, 42(5):1735-1747.

[46]Tian, Y., Zou, B., Yang, L., et al., 2011. High molecular weight persimmon tannin ameliorates cognition deficits and attenuates oxidative damage in senescent mice induced by D-galactose. Food Chem. Toxicol., 49(8):1728-1736.

[47]Toyama, K., Sugiyama, S., Oka, H., et al., 2010. Exercise therapy correlates with improving renal function through modifying lipid metabolism in patients with cardiovascular disease and chronic kidney disease. J. Cardiol., 56(2):142-146.

[48]Wang, C.P., Wang, Y., Wang, X., et al., 2011. Mulberroside a possesses potent uricosuric and nephroprotective effects in hyperuricemic mice. Planta Med., 77(8):786-794.

[49]Wicker, T., Robertson, J.S., Schulze, S.R., et al., 2005. The repetitive landscape of the chicken genome. Genome Res., 15(1):126-136.

[50]Wirleitner, B., Neurauter, G., Nagl, M., et al., 2004. Down-regulatory effect of N-chlorotaurine on tryptophan degradation and neopterin production in human PBMC. Immunol. Lett., 93(2-3):143-149.

[51]Wu, X., Kong, X., Zhou, Y., et al., 2012. Sesamin exerts renoprotective effects by enhancing NO bioactivity in renovascular hypertensive rats fed with high-fat-sucrose diet. Eur. J. Pharmacol., 683(1-3):231-237.

[52]Yan, X., 2015. Molecular nutrition: basic understanding of the digestion, absorption, and metabolism of nutrients. J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.), 16(6):413-416.