Full Text:   <2362>

CLC number: S855

On-line Access: 

Received: 2006-03-24

Revision Accepted: 2006-05-08

Crosschecked: 0000-00-00

Cited: 5

Clicked: 4272

Citations:  Bibtex RefMan EndNote GB/T7714

-   Go to

Article info.
1. Reference List
Open peer comments

Journal of Zhejiang University SCIENCE B 2006 Vol.7 No.8 P.660-664

http://doi.org/10.1631/jzus.2006.B0660


Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks


Author(s):  HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning

Affiliation(s):  Department of Veterinary Microbiology, University of Agriculture, Faisalabad 38040, Pakistan; more

Corresponding email(s):   mudasserhabib@yahoo.com

Key Words:  Infectious bursal disease virus (IBDV), Binary ethylenimine (BEI), Formaldehyde, Immune response


HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning. Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks[J]. Journal of Zhejiang University Science B, 2006, 7(8): 660-664.

@article{title="Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks",
author="HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning",
journal="Journal of Zhejiang University Science B",
volume="7",
number="8",
pages="660-664",
year="2006",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2006.B0660"
}

%0 Journal Article
%T Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks
%A HABIB Mudasser
%A HUSSAIN Iftikhar
%A IRSHAD Hamid
%A YANG Zong-zhao
%A SHUAI Jiang-bing
%A CHEN Ning
%J Journal of Zhejiang University SCIENCE B
%V 7
%N 8
%P 660-664
%@ 1673-1581
%D 2006
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2006.B0660

TY - JOUR
T1 - Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks
A1 - HABIB Mudasser
A1 - HUSSAIN Iftikhar
A1 - IRSHAD Hamid
A1 - YANG Zong-zhao
A1 - SHUAI Jiang-bing
A1 - CHEN Ning
J0 - Journal of Zhejiang University Science B
VL - 7
IS - 8
SP - 660
EP - 664
%@ 1673-1581
Y1 - 2006
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2006.B0660


Abstract: 
infectious bursal disease virus (IBDV) was inactivated by two different chemicals—formaldehyde and binary ethylenimine (BEI). formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

Reference

[1] Bahnemann, H.G., 1990. Inactivation of viral antigens for vaccine preparation with particular reference to the application of binary ethylenimine. Vaccine, 8(4):299-303.

[2] Blackburn, N.K., Besselaar, T.G., 1991. A study of the effect of chemical inactivants on the epitopes of Rift Valley fever virus glycoproteins using monoclonal antibodies. J. Virol. Methods, 33(3):367-374.

[3] Box, P., 1989. High maternal antibodies help chicks beat virulent strains. World Poultry, 53:17-19.

[4] Brown, F., 1995. Vaccination today and tomorrow. Biosci. Rep., 15(6):493-502.

[5] Buonavoglia, C., Iovane, G., Trani, L.D., Falcone, F., Orefice, L., Di Trani, L., 1988a. Evaluation of the immunogenicity in pigs guineapigs and chickens of an inactivated porcine parvovirus vaccine. Acta Medica Veterinaria, 34(2-3):445-452.

[6] Buonavoglia, C., Fioretti, A., Tollis, M., Menna, F., Papparella, V., 1988b. A preliminary vaccine potency trial of a Newcastle disease virus inactivated with binary ethylenimine. Vet. Res. Comm., 12(2-3):195-197.

[7] Dobos, P., Hill, B.J., Hallett, R., Kells, D.T., Becht, H., Teninges, D., 1979. Biophysical and biochemical characterization of five animal viruses with bisegmented double-stranded RNA genomes. J. Virol., 32(2):593-605.

[8] Habib, M., Hussain, I., Fang, W.H., Rajput, Z.I., Yang, Z.Z., Irshad, H., 2006. Inactivation of infectious bursal disease virus by binary ethylenimine and formalin. J. Zhejiang Univ. SCIENCE B, 7(4):320-323.

[9] Ismail, N.M., Saif, Y.M., Moorhead, P.D., 1988. Lack of pathogenicity of five serotype 2 infectious bursal disease viruses in chickens. Avian Dis., 32(4):757-759.

[10] Jackwood, D.J., Saif, Y.M., Hughes, J.H., 1982. Characteristics and serologic studies of two serotypes of infectious bursal disease virus in turkeys. Avian Dis., 26(4):871-882.

[11] Kibenge, F.S., Dhillon, A.S., Russell, R.G., 1988. Biochemistry and immunology of infectious bursal disease virus. J. Gen. Virol., 69(Pt 8):1757-1775.

[12] Kyvsgaard, N.C., Hoier, R., Bruck, I., Nansen, P., 1997. Effect of two virus inactivation methods: electron beam irradiation and binary ethylenimine treatment on determination of reproductive hormones in equine plasma. Acta Vet. Scand., 138(3):225-233.

[13] Lukert, P.D., Saif, Y.M., 1997. Infectious Bursal Disease. In: Calnek, B.W., Barnes, B.W., Beard, C.W., McDougald, L.R., Saif, Y.M. (Eds.), Diseases of Poultry, 10th Ed. Iowa State University Press, Ames, p.721-738.

[14] Lukert, P.D., Saif, Y.M., 2003. Infectious Bursal Disease. In: Saif, Y.M., Barnes, H.J., Glisson, J.R., Fadly, A.M., McDougald, L.R., Swayne, D.E. (Eds.), Diseases of Poultry, 11th Ed. Iowa State University Press, Ames, IO, p.161-179.

[15] McFerran, J.B., McNulty, M.S., McKillop, E.R., Connor, T.J., McCracken, R.M., Collins, D.S., Allan, G.M., 1980. Isolation and serological studies with infectious bursal disease viruses from fowl, turkeys and ducks: demonstration of a second serotype. Avian Pathol., 9:395-404.

[16] Özel, M., Gelderblom, H., 1985. Capsid symmetry of viruses of the proposed birnavirus group. Arch. Virol., 84(3-4):149-161.

[17] Reddy, Y.K., Koteeswaren, A., Dorairajan, N., 1977. Pattern of infectious bursal disease in commercial white Leghorn chicken. Indian Vet. J., 74:1019-1021.

[18] Reed, L.J., Muench, H., 1938. A simple method of estimating fifty percent endpoints. Amer. J. Hyg., 27:493-497.

[19] Rehman, S.U., Ashfaque, M., Javed, S., 1994. Infectious bursal disease antibody titration using indirect Hemagglutination test. Pak. Vet. J., 14:101-103.

[20] Sawada, T., Rimler, R.B., Rhoades, K.R., 1982. Indirect hemagglutination test that uses glutaraldehyde-fixed sheep erythrocytes sensitized with extract antigens for detection of Pasteurella antibody. J. Clin. Microbiol., 15(5):752-756.

[21] Sulochana, S., Lalithakunjamma, C.R., 1991. Infectious bursal disease in Kerala. Cheiron., 20:180-183.

[22] van den Berg, T.P., 2000. Acute infectious bursal disease in poultry: a review. Avian Pathol., 29(3):175-194.

[23] Zierenberg, K., Raue, R., Nieper, H., Islam, M.R., Eterradossi, N., Toquin, D., Müller, H., 2004. Generation of serotype 1/serotype 2 reassortant viruses of the infectious bursal disease virus and their investigation in vitro and in vivo. Virus Res., 105(1):23-34.

Open peer comments: Debate/Discuss/Question/Opinion

<1>

Please provide your name, email address and a comment





Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - 2022 Journal of Zhejiang University-SCIENCE