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Received: 2006-03-24

Revision Accepted: 2006-05-08

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Journal of Zhejiang University SCIENCE B 2006 Vol.7 No.8 P.660-664

http://doi.org/10.1631/jzus.2006.B0660


Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks


Author(s):  HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning

Affiliation(s):  Department of Veterinary Microbiology, University of Agriculture, Faisalabad 38040, Pakistan; more

Corresponding email(s):   mudasserhabib@yahoo.com

Key Words:  Infectious bursal disease virus (IBDV), Binary ethylenimine (BEI), Formaldehyde, Immune response


HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning. Immunogenicity of formaldehyde and binary ethylenimine inactivated infectious bursal disease virus in broiler chicks[J]. Journal of Zhejiang University Science B, 2006, 7(8): 660-664.

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author="HABIB Mudasser, HUSSAIN Iftikhar, IRSHAD Hamid, YANG Zong-zhao, SHUAI Jiang-bing, CHEN Ning",
journal="Journal of Zhejiang University Science B",
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pages="660-664",
year="2006",
publisher="Zhejiang University Press & Springer",
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A1 - YANG Zong-zhao
A1 - SHUAI Jiang-bing
A1 - CHEN Ning
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Abstract: 
infectious bursal disease virus (IBDV) was inactivated by two different chemicals—formaldehyde and binary ethylenimine (BEI). formaldehyde was used at 0.1% and 0.2%, while BEI was used at concentrations of 0.001 and 0.002 mol/L. These four vaccines were tested for their efficiency in generating humoral immune response in different groups of broiler chicks. Both BEI-inactivated vaccines gave relatively higher antibody titers and were almost twice as efficient as formaldehyde-inactivated ones.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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