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Received: 2015-10-12

Revision Accepted: 2015-12-02

Crosschecked: 2016-04-11

Cited: 3

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Jian-an Wang


Na Zhang


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Journal of Zhejiang University SCIENCE B 2016 Vol.17 No.5 P.333-341


Multifunctional protein: cardiac ankyrin repeat protein

Author(s):  Na Zhang, Xiao-jie Xie, Jian-an Wang

Affiliation(s):  Cardiovascular Key Lab of Zhejiang Province, Department of Cardiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

Corresponding email(s):   jian_an_wang@yahoo.com

Key Words:  Cardiac ankyrin repeat protein (CARP), Cardiovascular disease, Cardiac development

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Na Zhang, Xiao-jie Xie, Jian-an Wang. Multifunctional protein: cardiac ankyrin repeat protein[J]. Journal of Zhejiang University Science B, 2016, 17(5): 333-341.

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%T Multifunctional protein: cardiac ankyrin repeat protein
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%DOI 10.1631/jzus.B1500247

T1 - Multifunctional protein: cardiac ankyrin repeat protein
A1 - Na Zhang
A1 - Xiao-jie Xie
A1 - Jian-an Wang
J0 - Journal of Zhejiang University Science B
VL - 17
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EP - 341
%@ 1673-1581
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B1500247

cardiac ankyrin repeat protein (CARP) not only serves as an important component of muscle sarcomere in the cytoplasm, but also acts as a transcription co-factor in the nucleus. Previous studies have demonstrated that CARP is up-regulated in some cardiovascular disorders and muscle diseases; however, its role in these diseases remains controversial now. In this review, we will discuss the continued progress in the research related to CARP, including its discovery, structure, and the role it plays in cardiac development and heart diseases.

The authors discuss the discovery structure of ankyrin repeat protein . They also discuss the role of this protein in cardiac development and heart disease. It is a very concise and well organized review providing useful information about this protein to readers. This review was written by standard English and the logic is very clear and easy to follow.



Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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