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On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
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Citations: Bibtex RefMan EndNote GB/T7714
Haitao ZHU, Kaifa TANG, Guoqiang CHEN, Zhongwei LIU. Biomarkers in oral immunotherapy[J]. Journal of Zhejiang University Science B, 2022, 23(9): 705-731.
@article{title="Biomarkers in oral immunotherapy",
author="Haitao ZHU, Kaifa TANG, Guoqiang CHEN, Zhongwei LIU",
journal="Journal of Zhejiang University Science B",
volume="23",
number="9",
pages="705-731",
year="2022",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2200047"
}
%0 Journal Article
%T Biomarkers in oral immunotherapy
%A Haitao ZHU
%A Kaifa TANG
%A Guoqiang CHEN
%A Zhongwei LIU
%J Journal of Zhejiang University SCIENCE B
%V 23
%N 9
%P 705-731
%@ 1673-1581
%D 2022
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2200047
TY - JOUR
T1 - Biomarkers in oral immunotherapy
A1 - Haitao ZHU
A1 - Kaifa TANG
A1 - Guoqiang CHEN
A1 - Zhongwei LIU
J0 - Journal of Zhejiang University Science B
VL - 23
IS - 9
SP - 705
EP - 731
%@ 1673-1581
Y1 - 2022
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2200047
Abstract: food allergy (FA) is a global health problem that affects a large population, and thus effective treatment is highly desirable. oral immunotherapy (OIT) has been showing reasonable efficacy and favorable safety in most FA subjects. Dependable biomarkers are needed for treatment assessment and outcome prediction during OIT. Several immunological indicators have been used as biomarkers in OIT, such as skin prick tests, basophil and mast cell reactivity, T cell and B cell responses, allergen-specific antibody levels, and cytokines. Other novel indicators also could be potential biomarkers. In this review, we discuss and assess the application of various immunological indicators as biomarkers for OIT.
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