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Received: 2023-08-31
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Advanced Strategies for 3D-Printed Neural Scaffolds: Materials, Structure, and Nerve Remodeling
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Jian He, Liang Qiao, Jiuhong Li, Junlin Lu, Zhouping Fu, Jiafang Chen, Xiangchun Zhang, Xulin Hu. Advanced Strategies for 3D-Printed Neural Scaffolds: Materials, Structure, and Nerve Remodeling[J]. Journal of Zhejiang University Science D, 2024, 7(5): 747-770.
@article{title="Advanced Strategies for 3D-Printed Neural Scaffolds: Materials,
Structure, and Nerve Remodeling",
author="Jian He, Liang Qiao, Jiuhong Li, Junlin Lu, Zhouping Fu, Jiafang Chen, Xiangchun Zhang, Xulin Hu",
journal="Journal of Zhejiang University Science D",
volume="7",
number="5",
pages="747-770",
year="2024",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-024-00291-5"
}
%0 Journal Article
%T Advanced Strategies for 3D-Printed Neural Scaffolds: Materials,
Structure, and Nerve Remodeling
%A Jian He
%A Liang Qiao
%A Jiuhong Li
%A Junlin Lu
%A Zhouping Fu
%A Jiafang Chen
%A Xiangchun Zhang
%A Xulin Hu
%J Journal of Zhejiang University SCIENCE D
%V 7
%N 5
%P 747-770
%@ 1869-1951
%D 2024
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-024-00291-5
TY - JOUR
T1 - Advanced Strategies for 3D-Printed Neural Scaffolds: Materials,
Structure, and Nerve Remodeling
A1 - Jian He
A1 - Liang Qiao
A1 - Jiuhong Li
A1 - Junlin Lu
A1 - Zhouping Fu
A1 - Jiafang Chen
A1 - Xiangchun Zhang
A1 - Xulin Hu
J0 - Journal of Zhejiang University Science D
VL - 7
IS - 5
SP - 747
EP - 770
%@ 1869-1951
Y1 - 2024
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-024-00291-5
Abstract: nerve regeneration holds significant potential in the treatment of various skeletal and neurological disorders
to restore lost sensory and motor functions. The potential of nerve regeneration in ameliorating neurological
diseases and injuries is critical to human health. Three-dimensional (3D) printing offers versatility and precision
in the fabrication of neural scaffolds. Complex neural structures such as neural tubes and scaffolds can be
fabricated via 3D printing. This review comprehensively analyzes the current state of 3D-printed neural
scaffolds and explores strategies to enhance their design. It highlights therapeutic strategies and structural
design involving neural materials and stem cells. First, nerve regeneration materials and their fabrication
techniques are outlined. The applications of conductive materials in neural scaffolds are reviewed, and their
potential to facilitate neural signal transmission and regeneration is highlighted. Second, the progress in
3D-printed neural scaffolds applied to the peripheral and central nerves is comprehensively evaluated, and
their potential to restore neural function and promote the recovery of different nervous systems is emphasized.
In addition, various applications of 3D-printed neural scaffolds in peripheral and neurological diseases, as well
as the design strategies of multifunctional biomimetic scaffolds, are discussed.
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