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Journal of Zhejiang University SCIENCE A 2002 Vol.3 No.3 P.378-380

http://doi.org/10.1631/jzus.2002.0378


Evaluation of cilazapril in vasovagal syncope treatment


Author(s):  HAN Yang, JIANG Wei-li, JIN Mei-zhen, GE Wei, CHEN Tian-zhi

Affiliation(s):  1st Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China

Corresponding email(s): 

Key Words:  Vasovagal syncope (VVS), Cilazapril, Blood pressure & heart rate, Tilt table test


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HAN Yang, JIANG Wei-li, JIN Mei-zhen, GE Wei, CHEN Tian-zhi. Evaluation of cilazapril in vasovagal syncope treatment[J]. Journal of Zhejiang University Science A, 2002, 3(3): 378-380.

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author="HAN Yang, JIANG Wei-li, JIN Mei-zhen, GE Wei, CHEN Tian-zhi",
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volume="3",
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pages="378-380",
year="2002",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2002.0378"
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%A JIANG Wei-li
%A JIN Mei-zhen
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T1 - Evaluation of cilazapril in vasovagal syncope treatment
A1 - HAN Yang
A1 - JIANG Wei-li
A1 - JIN Mei-zhen
A1 - GE Wei
A1 - CHEN Tian-zhi
J0 - Journal of Zhejiang University Science A
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2002.0378


Abstract: 
Objective: to evaluate cilazapril in vasovagal syncope treatment. Method: eighty-six cases of VVS patients found positive in TTT tilt were medicated with 2.5 mg cilazapril daily for three months and followed up by TTT. Results: seven cases quit due to cough or unexplained reason; 79 VVS patients had no more fainting spells; 75.95% of TTT results of patients changed to negative after 3 months therapy. The before and after cilazapril treatment average blood pressures (taken in lying position) were 121/73 mm Hg (1 mm Hg=0.133kPa) and 120/76 mm Hg respectively (P>0.05); and mean heart rates were 68.63±12.37/min and 70.13±13.15/min respectively with no significant changes (P>0.05). Conclusion: cilazapril was effective in treatment of VVS; did not affect normal blood pressure and heart rate; was safe; and had little side effect.

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Reference

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[8] Zeng Chunyu, Liu Guangyao, Wang Xuekai et al., 1998. Discussion of therapeutic observation and machinism in elderly VVS with enapril treatment. Chin J Geriatrics, 17(3):184-185(in Chinese, with English abstract).

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