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On-line Access: 2024-08-27
Received: 2023-10-17
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Inflammatory granuloma of the trachea: a rare case with Epstin-Barr virus infection
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Zhaodi WANG, Xuan LU, Yunmei YANG, Yuanqiang LU. Inflammatory granuloma of the trachea: a rare case with Epstin-Barr virus infection[J]. Journal of Zhejiang University Science B, 2023, 24(6): 539-542.
@article{title="Inflammatory granuloma of the trachea: a rare case with Epstin-Barr virus infection",
author="Zhaodi WANG, Xuan LU, Yunmei YANG, Yuanqiang LU",
journal="Journal of Zhejiang University Science B",
volume="24",
number="6",
pages="539-542",
year="2023",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2300024"
}
%0 Journal Article
%T Inflammatory granuloma of the trachea: a rare case with Epstin-Barr virus infection
%A Zhaodi WANG
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%J Journal of Zhejiang University SCIENCE B
%V 24
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%D 2023
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2300024
TY - JOUR
T1 - Inflammatory granuloma of the trachea: a rare case with Epstin-Barr virus infection
A1 - Zhaodi WANG
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A1 - Yunmei YANG
A1 - Yuanqiang LU
J0 - Journal of Zhejiang University Science B
VL - 24
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%@ 1673-1581
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B2300024
Abstract: epstein-Barr virus (EBV), a double-stranded DNA virus with an envelope, is a ubiquitous pathogen that is prevalent in humans, although most people who contract it do not develop symptoms (Kerr, 2019). While the primary cells EBV attacks are epithelial cells and B lymphocytes, its target range expands to a variety of cell types in immunodeficient hosts. Serological change occurs in 90% of infected patients. Therefore, immunoglobulin M (IgM) and IgG, serologically reactive to viral capsid antigens, are reliable biomarkers for the detection of acute and chronic EBV infections (Cohen, 2000). Symptoms of EBV infection vary according to age and immune status. Young patients with primary infection may present with infectious mononucleosis; there is a typical triad of symptoms including fever, angina, and lymphadenectasis (Houen and Trier, 2021). In immunocompromised patients, response after EBV infection may be atypical, with unexplained fever. The nucleic acid of EBV can be detected to confirm whether high-risk patients are infected (Smets et al., 2000). EBV is also associated with the occurrence of certain tumors (such as lymphoma and nasopharyngeal carcinoma) because it transforms host cells (Shannon-Lowe et al., 2017; Tsao et al., 2017).
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